Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
| ▸ | TAF1 | P21675 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.30 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537709 | 0.78 | POLB (0.47) | POLBKDM4EBRD1TAF1BRPF1 | |
| SCHEMBL2648820 | 0.78 | SLC6A4 (0.34) | SLC22A12 | |
| SCHEMBL9518709 | 0.75 | CYSLTR2 (0.37) | — | |
| SCHEMBL17537710 | 0.74 | POLB (0.45) | POLBKDM4E | |
| SCHEMBL17537960 | 0.74 | POLB (0.45) | POLBKDM4EBRD1TAF1BRPF1 | |
| SCHEMBL17537711 | 0.74 | POLB (0.45) | POLBKDM4EBRD1TAF1BRPF1 | |
| SCHEMBL11648609 | 0.74 | POLB (0.43) | POLBKDM4EBRD1TAF1BRPF1 | |
| SCHEMBL2648604 | 0.73 | CYP4F2 (0.52) | POLBKDM4E | |
| SCHEMBL17537958 | 0.73 | POLB (0.44) | POLBKDM4EBRD1TAF1BRPF1 | |
| SCHEMBL17537712 | 0.72 | POLB (0.42) | POLBKDM4EBRD1TAF1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |