Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | OGA | O60502 | 11/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650754 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2OGACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1343127 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2OGACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1343375 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2OGAACKR3OPRK1 | |
| SCHEMBL2652027 | 0.78 | OGA (0.44) | SMN1; SMN2OGACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2651301 | 0.77 | GAA (0.36) | SMN1; SMN2CYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL1343032 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2OGAACKR3 | |
| SCHEMBL1341711 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2OGAACKR3 | |
| SCHEMBL1342754 | 0.74 | OGA (0.51) | SMN1; SMN2OGA | |
| SCHEMBL1343227 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2OGAACKR3 | |
| SCHEMBL1343325 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2OGAACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |