SCHEMBL26508358

SCHEMBL26508358

c1cc(-c2ccc3c(c2)sc2ccccc23)c2c(c1)oc1cccc(-n3c4ccccc4c4cc5c(cc43)sc3ccccc35)c12

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.38
ALOX5 P09917 1/20 0.36
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26506894 0.95 PRKDC (0.41) PRKDCALOX5ALDH1A1MAPTHPGD
SCHEMBL26507705 0.91 PRKDC (0.40) PRKDCALOX5
SCHEMBL26512935 0.90 ALOX5 (0.39) PRKDCALOX5ALDH1A1MAPTHPGD
SCHEMBL26509343 0.89 PRKDC (0.35) PRKDCALOX5
SCHEMBL26540339 0.87 PRKDC (0.40) PRKDCALOX5
SCHEMBL25937919 0.85 PRKDC (0.34) PRKDCALOX5
SCHEMBL25930179 0.85 PRKDC (0.34) PRKDCALOX5
SCHEMBL25937676 0.84 PRKDC (0.34) PRKDCALOX5ALDH1A1MAPTHPGD
SCHEMBL25117314 0.84 PRKDC (0.30) PRKDC
SCHEMBL26511307 0.84 ALOX5 (0.43) PRKDCALOX5ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed