Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640328 | 0.82 | TERT (0.40) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL14971478 | 0.82 | HSD17B10 (0.44) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL24577905 | 0.81 | KDM4E (0.47) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL7343230 | 0.81 | TERT (0.40) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL1968157 | 0.81 | SMN1; SMN2 (0.44) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL24754097 | 0.78 | SMN1; SMN2 (0.41) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL23896279 | 0.77 | TERT (0.40) | TERTGSK3BSMN1; SMN2ALDH1A1 | |
| SCHEMBL14971479 | 0.75 | TERT (0.39) | TERTLMNAGSK3BDYRK1AWNT1 | |
| SCHEMBL26511083 | 0.74 | GAA (0.46) | TERTLMNAALDH1A1 | |
| SCHEMBL12521944 | 0.73 | TSHR (0.59) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205892-A1 | CDK INHIBITORS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023193085-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) | 2023-10-12 | — | — | WO | disclosed |