SCHEMBL26512210

SCHEMBL26512210

Cc1ccc(C(C)C)c(N(C)S(C)(=O)=O)n1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
PTK2 Q05397 7/20 0.34
GAA P10253 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
POLB P06746 1/20 0.32
USP1 O94782 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.31
SRPK2 P78362 1/20 0.30
SRPK1 Q96SB4 1/20 0.30
GLO1 Q04760 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24498127 0.82 ALDH1A1 (0.32) ALDH1A1HPGDHSP90AA1HSP90AB1POLB
SCHEMBL24498234 0.79 GAA (0.41) ALDH1A1PTK2GAAPOLBMAPT
SCHEMBL21725559 0.78 CYP1A2 (0.38) ALDH1A1HPGDMAPT
SCHEMBL26114239 0.76 GAA (0.39) PTK2GAAPOLBMAPTGLO1
SCHEMBL29686818 0.76 GAA (0.39) PTK2GAAPOLBMAPTGLO1
SCHEMBL26518522 0.75 PTK2 (0.44) PTK2GAAPDE10A
SCHEMBL24498307 0.73 PTK2 (0.39) PTK2GAAMAPTGLO1PDE10A
SCHEMBL26513569 0.73 PTK2 (0.41) PTK2POLBL3MBTL1MAPTSRPK2
SCHEMBL1627151 0.72 ALDH1A1 (0.36) ALDH1A1PTK2GAAPOLBL3MBTL1
SCHEMBL26511009 0.72 PTK2 (0.36) ALDH1A1PTK2GAAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed