SCHEMBL26512929

SCHEMBL26512929

CCC1(CC)c2ccccc2-c2c1c1c(c3cc(OC)c(OC)cc23)OC(c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)(c2cc(F)cc(F)c2)C=C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
WHR1 P49842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26512986 0.96 MEN1 (0.31)
SCHEMBL26512920 0.95 ABCG2 (0.31) WHR1
SCHEMBL26512933 0.94 WHR1 (0.33) WHR1
SCHEMBL26512983 0.92 MEN1 (0.32)
SCHEMBL26512886 0.92 NTSR1 (0.33) WHR1
SCHEMBL26512820 0.92
SCHEMBL26512924 0.91 HSP90AA1 (0.31) WHR1
SCHEMBL26512939 0.91 WHR1 (0.31) WHR1
SCHEMBL26512955 0.90
SCHEMBL26512661 0.90 WHR1 (0.32) WHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323197-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-10-12 US disclosed
US-20230323197-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-10-12 US disclosed