Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 4/20 | 0.35 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512968 | 0.94 | NTSR1 (0.36) | NTSR1WHR1SIRT1ABCG2KDM4E | |
| SCHEMBL26512856 | 0.93 | TLR9 (0.32) | SIRT1ABCG2NPSR1MAPTTLR9 | |
| SCHEMBL26512701 | 0.92 | WHR1 (0.35) | NTSR1WHR1SIRT1ABCG2KDM4E | |
| SCHEMBL26512964 | 0.90 | NTSR1 (0.32) | NTSR1TLR9 | |
| SCHEMBL26512969 | 0.88 | WHR1 (0.38) | WHR1ABCG2KDM4EMAPT | |
| SCHEMBL26513292 | 0.87 | NTSR1 (0.36) | NTSR1KDM4ESTAT6NPSR1MAPT | |
| SCHEMBL26512855 | 0.87 | — | — | |
| SCHEMBL26512858 | 0.86 | MAPT (0.38) | KDM4ENPSR1MAPTTLR9 | |
| SCHEMBL26512972 | 0.86 | MAPT (0.34) | NTSR1WHR1KDM4EMAPT | |
| SCHEMBL26512704 | 0.86 | MAPK1 (0.37) | NTSR1WHR1SIRT1ABCG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |