SCHEMBL26513478

SCHEMBL26513478

c1ccc(-c2ccc(-c3ccc4sc5cc(-n6c7ccccc7c7ccccc76)ccc5c4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
PIM3 Q86V86 1/20 0.39
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LIMK1 P53667 2/20 0.36
HDAC4 P56524 1/20 0.36
GPR3 P46089 1/20 0.35
F9 P00740 2/20 0.34
TSPO P30536 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
ROCK1 Q13464 1/20 0.33
CYP1A2 P05177 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26348704 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL26514880 0.93 KDM4E (0.39) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL2628347 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL25941312 0.93 KDM4E (0.41) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL26511360 0.93 MAPT (0.41) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL10348849 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL20277233 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL23505151 0.92 KDM4E (0.40) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL20633753 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMPIM3ALDH1A1
SCHEMBL20871473 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMPIM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed