Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539727 | 1.00 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28075454 | 1.00 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28075368 | 1.00 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| Ammonia Solution, Strong SCHEMBL3120827 | 0.97 | TSHR (0.50) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL2010651 | 0.97 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL1608237 | 0.89 | — | — | |
| SCHEMBL18503260 | 0.83 | TSHR (0.41) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL18419060 | 0.83 | TSHR (0.41) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL17954034 | 0.82 | ACLY (0.46) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL9211224 | 0.80 | TSHR (0.48) | TSHRALDH1A1MAPTABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192873-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-05 | — | — | WO | disclosed |