Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | DNM1L | O00429 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343401 | 0.89 | MEN1 (0.43) | PIM1PIM3LMNAMEN1KMT2A | |
| SCHEMBL1340533 | 0.88 | PIM1 (0.47) | PIM1PIM3PIM2GAALMNA | |
| SCHEMBL1342299 | 0.84 | PIM1 (0.56) | PIM1PIM3PIM2DHFREGFR | |
| SCHEMBL2661569 | 0.80 | LMNA (0.41) | GAADHFREGFRLMNAHRH3 | |
| SCHEMBL1341174 | 0.79 | MAPT (0.41) | PIM1PIM3PIM2DNM1L | |
| SCHEMBL1343787 | 0.77 | MAPT (0.39) | PIM1PIM3PIM2MEN1KMT2A | |
| SCHEMBL1340899 | 0.75 | MAPT (0.48) | PIM1PIM3GAALMNA | |
| SCHEMBL1340960 | 0.74 | LMNA (0.44) | GAADHFREGFRLMNAHRH3 | |
| SCHEMBL1341384 | 0.74 | MAPT (0.43) | PIM1PIM3PIM2DNM1L | |
| SCHEMBL1343127 | 0.74 | SMN1; SMN2 (0.50) | LMNAMEN1KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |