SCHEMBL26514852

SCHEMBL26514852

c1ccc(-c2ccc3c(c2)sc2cc(-n4c5ccccc5c5cc(-c6ccccc6)ccc54)ccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSPO P30536 2/20 0.39
LIMK1 P53667 2/20 0.36
HDAC4 P56524 1/20 0.36
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DNM1 Q05193 1/20 0.34
PIM3 Q86V86 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PIK3CA P42336 1/20 0.33
PI4KA P42356 1/20 0.33
PI4KB Q9UBF8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27411932 0.99 L3MBTL1 (0.45) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL26514254 0.97 KDM4E (0.40) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL26060210 0.97 L3MBTL1 (0.47) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL25941312 0.96 KDM4E (0.41) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL26513571 0.96 LIMK1 (0.39) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL20633753 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL20871473 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL26796525 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL25941225 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TSPOLIMK1
SCHEMBL17322661 0.94 L3MBTL1 (0.50) KDM4EATML3MBTL1TSPOLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed