Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 10/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | GIPR | P48546 | 5/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.33 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.33 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.33 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.33 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650817 | 0.94 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL2652191 | 0.91 | GCGR (0.47) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL2661428 | 0.90 | GCGR (0.47) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL6748418 | 0.89 | GCGR (0.48) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL2650883 | 0.89 | GCGR (0.49) | SMN1; SMN2MAPTGCGROPRM1OPRK1 | |
| SCHEMBL6751674 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL2651922 | 0.88 | NPSR1 (0.50) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL6753872 | 0.87 | MAPT (0.45) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL6751732 | 0.87 | MAPT (0.45) | SMN1; SMN2MAPTHTTNPSR1GAA | |
| SCHEMBL2650819 | 0.83 | OPRM1 (0.40) | SMN1; SMN2MAPTHTTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | claimed |