Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651631 | 0.84 | CCNE1 (0.35) | GRM4GAASIRT4 | |
| SCHEMBL1341709 | 0.82 | CCNE1 (0.33) | GRM4GAASIRT4 | |
| SCHEMBL1341473 | 0.79 | CCNE1 (0.39) | CRHBPCRHR2 | |
| SCHEMBL2650482 | 0.78 | IDH1 (0.35) | — | |
| SCHEMBL2651114 | 0.77 | — | — | |
| SCHEMBL1343129 | 0.76 | CCNE1 (0.35) | GRM4CRHBPCRHR2 | |
| SCHEMBL1342422 | 0.74 | CDK2 (0.34) | GAACRHBPCRHR2 | |
| SCHEMBL1342336 | 0.73 | CCNE1 (0.38) | GAA | |
| SCHEMBL1342238 | 0.73 | SMN1; SMN2 (0.35) | GAA | |
| SCHEMBL1341950 | 0.73 | MAPT (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |