Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.35 |
| ▸ | CDK2 | P24941 | 6/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341709 | 0.97 | CCNE1 (0.33) | CCNE1CDK2CDK5GRM4SIRT4 | |
| SCHEMBL1341473 | 0.93 | CCNE1 (0.39) | CCNE1CDK2CDK5ALDH1A1KMT2A | |
| SCHEMBL1342422 | 0.88 | CDK2 (0.34) | CCNE1CDK2CDK5GAAIDH2 | |
| SCHEMBL1342238 | 0.87 | SMN1; SMN2 (0.35) | CCNE1CDK2CDK5KMT2AGAA | |
| SCHEMBL1341866 | 0.85 | MAPT (0.40) | CCNE1CDK2CDK5ALDH1A1KMT2A | |
| SCHEMBL1341979 | 0.85 | RXFP1 (0.33) | CCNE1CDK2CDK5KMT2AIDH2 | |
| SCHEMBL1341950 | 0.85 | MAPT (0.34) | CCNE1CDK2CDK5KMT2AGAA | |
| SCHEMBL2651630 | 0.84 | GRM4 (0.33) | GRM4SIRT4GAA | |
| SCHEMBL1341913 | 0.84 | CCNE1 (0.38) | CCNE1CDK2CDK5CNR1CNR2 | |
| SCHEMBL1342141 | 0.83 | SIRT4 (0.35) | CCNE1CDK2CDK5GRM4SIRT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |