Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353667 | 0.85 | NOTUM (0.47) | NOTUMSMN1; SMN2 | |
| SCHEMBL6648174 | 0.85 | NOTUM (0.47) | NOTUMSMN1; SMN2 | |
| SCHEMBL16385108 | 0.85 | NOTUM (0.47) | NOTUMSMN1; SMN2 | |
| SCHEMBL16353535 | 0.85 | NOTUM (0.47) | NOTUMSMN1; SMN2 | |
| SCHEMBL21172497 | 0.83 | NOTUM (0.61) | NOTUMLMNAMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL21172644 | 0.83 | NOTUM (0.61) | NOTUMLMNAMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL26517034 | 0.81 | NOTUM (0.51) | NOTUMALDH1A1TSHRMTNR1AMTNR1B | |
| SCHEMBL23917172 | 0.81 | KDM4E (0.59) | NOTUMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17619538 | 0.81 | NPC1 (0.62) | NOTUML3MBTL1GAAMTNR1AMTNR1B | |
| SCHEMBL21172618 | 0.79 | NOTUM (0.49) | NOTUMALDH1A1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192375-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. (US) | 2023-10-05 | — | — | WO | disclosed |