Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.41 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21172644 | 0.85 | NOTUM (0.61) | NOTUMHSD17B3SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL21172497 | 0.85 | NOTUM (0.61) | NOTUMHSD17B3SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL21172618 | 0.81 | NOTUM (0.49) | NOTUMSMN1; SMN2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL26517033 | 0.81 | NOTUM (0.49) | NOTUMSMN1; SMN2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL23917466 | 0.81 | NOTUM (0.49) | NOTUMSMN1; SMN2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL23917198 | 0.80 | NOTUM (0.48) | NOTUMHSD17B3SMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL7352202 | 0.80 | AVPR2 (0.56) | NOTUMHSD17B3SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL16353667 | 0.79 | NOTUM (0.47) | NOTUMSMN1; SMN2 | |
| SCHEMBL23917280 | 0.79 | NOTUM (0.47) | NOTUMHSD17B3SMN1; SMN2ALDH1A1MTNR1A | |
| SCHEMBL16353535 | 0.79 | NOTUM (0.47) | NOTUMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192375-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. (US) | 2023-10-05 | — | — | WO | disclosed |