Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 15/20 | 0.40 |
| ▸ | GIPR | P48546 | 4/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661770 | 0.86 | PPARG (0.52) | HDAC1HDAC6GCGRGIPRSIRT2 | |
| SCHEMBL2652504 | 0.82 | KDM4E (0.43) | GCGRGIPRJAK2JAK1TYK2 | |
| SCHEMBL2651576 | 0.82 | EGLN1 (0.48) | GCGR | |
| SCHEMBL2651098 | 0.81 | KDM4E (0.46) | GCGRGIPRKDM4ETDP1 | |
| SCHEMBL2652127 | 0.80 | GCGR (0.39) | GCGRGIPRKDM4E | |
| SCHEMBL2652463 | 0.80 | PTGER4 (0.51) | HDAC1HDAC6SIRT2 | |
| SCHEMBL2653945 | 0.80 | GCGR (0.45) | GCGR | |
| SCHEMBL7113992 | 0.78 | SMN1; SMN2 (0.43) | GCGRJAK2JAK1TYK2JAK3 | |
| SCHEMBL2653039 | 0.77 | MRGPRX1 (0.51) | GCGR | |
| SCHEMBL2651921 | 0.75 | VDR (0.43) | GCGRGIPRJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212119-A1 | Novel glucagon receptor antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-11-13 | — | — | US | disclosed |
| WO-2003053938-A1 | BENZIMIDAZOLS AND INDOLS AS GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTEN | NOVO NORDISK A/S (DK) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212119-A1 | Novel glucagon receptor antagonists/inverse agonists | GLP1R, GCGR, GIPR | HDAC1 3760/4885HDAC6 3834/4885GCGR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.