SCHEMBL26519237

SCHEMBL26519237

CN(c1ccccc1F)S(C)(=O)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.43
ALOX5AP P20292 1/20 0.43
FEN1 P39748 1/20 0.43
PER2 O15055 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
CYP19A1 P11511 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
C5AR1 P21730 1/20 0.40
POLB P06746 1/20 0.40
ESR1 P03372 1/20 0.40
CDK1 P06493 1/20 0.39
CDK2 P24941 1/20 0.39
CDK5 Q00535 1/20 0.39
CDC42BPA Q5VT25 1/20 0.39
SRPK1 Q96SB4 1/20 0.39
IRAK4 Q9NWZ3 1/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16914834 0.78 ALDH1A1 (0.45) KMT2AALDH1A1TSHRPER2L3MBTL1
SCHEMBL6017732 0.77 KMT2A (0.39) KMT2AALDH1A1TSHRALOX5APFEN1
SCHEMBL5143537 0.77 KMT2A (0.51) KMT2AALDH1A1TSHRL3MBTL1CYP19A1
SCHEMBL2760284 0.77 KMT2A (0.51) KMT2AALDH1A1TSHRPER2L3MBTL1
SCHEMBL14830079 0.76 DDB1 (0.39) KMT2AALDH1A1PER2C5AR1ESR1
Hydrochloric Acid SCHEMBL21048872 0.76 JAK2 (0.39) KMT2AALDH1A1TSHRALOX5APFEN1
SCHEMBL29373327 0.75 KMT2A (0.50) KMT2AALDH1A1TSHRALOX5APFEN1
SCHEMBL945647 0.75 KMT2A (0.50) KMT2AALDH1A1TSHRALOX5APFEN1
SCHEMBL1291268 0.75 KMT2A (0.50) KMT2AALDH1A1TSHRALOX5APFEN1
SCHEMBL2634649 0.75 KMT2A (0.50) KMT2AALDH1A1TSHRL3MBTL1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed