Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668742 | 0.95 | L3MBTL1 (0.47) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL22240727 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL22240718 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL22240578 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL24722551 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL24216851 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL24525936 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL24525932 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL22240736 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL22763990 | 0.92 | MEN1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257586-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE | LT Materials Co., Ltd. (KR) | 2023-10-11 | — | — | EP | disclosed |