Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.43 |
| ▸ | GIPR | P48546 | 3/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GCG | P01275 | 6/20 | 0.39 |
| ▸ | GLP1R | P43220 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752116 | 0.90 | GCGR (0.50) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL6754077 | 0.90 | GCG (0.47) | GCGRGIPRMCHR1GCGGLP1R | |
| SCHEMBL2651297 | 0.89 | GCGR (0.51) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL2650683 | 0.81 | GCGR (0.49) | GCGRGIPRGLP1R | |
| SCHEMBL4258400 | 0.81 | GCGR (0.54) | GCGRGIPRGCGGLP1R | |
| SCHEMBL2651183 | 0.81 | GCGR (0.55) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL2650947 | 0.80 | F2 (0.44) | GCGRGIPRMCHR1GCGGLP1R | |
| SCHEMBL2650834 | 0.79 | GCG (0.52) | GCGRGIPRGCGGLP1R | |
| SCHEMBL2651224 | 0.79 | GCGR (0.49) | GCGRGIPRGCGGLP1R | |
| SCHEMBL2664999 | 0.78 | GCGR (0.61) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | claimed |