Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.51 |
| ▸ | GIPR | P48546 | 4/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 2/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752116 | 0.93 | GCGR (0.50) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL2651183 | 0.92 | GCGR (0.55) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL2652068 | 0.89 | GCGR (0.43) | GCGRGIPRCXCR3MCHR1GLP1R | |
| SCHEMBL2651118 | 0.88 | GCGR (0.47) | GCGRGIPRGLP1R | |
| SCHEMBL7101508 | 0.86 | GCGR (0.45) | GCGRGIPRMCHR1GLP1R | |
| SCHEMBL2651291 | 0.85 | GCGR (0.73) | GCGRGIPRGLP1R | |
| SCHEMBL2650524 | 0.84 | GCGR (0.46) | GCGRGIPRCXCR3GLP1R | |
| SCHEMBL2650683 | 0.84 | GCGR (0.49) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL4095266 | 0.83 | GCGR (0.66) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2650786 | 0.82 | GCGR (0.42) | GCGRGIPRGLP1RADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |