Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.72 |
| ▸ | CCNK | O75909 | 1/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
| ▸ | CDK7 | P50613 | 1/20 | 0.72 |
| ▸ | CDK9 | P50750 | 1/20 | 0.72 |
| ▸ | CCNH | P51946 | 1/20 | 0.72 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.72 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.72 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.72 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 10/20 | 0.45 |
| ▸ | BTK | Q06187 | 7/20 | 0.45 |
| ▸ | BLK | P51451 | 3/20 | 0.45 |
| ▸ | ITK | Q08881 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113855 | 0.89 | CCNT1 (0.67) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL18122670 | 0.84 | CCNT1 (0.62) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL20550154 | 0.84 | CDK9 (1.00) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL18113959 | 0.84 | CDK9 (1.00) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL18122697 | 0.84 | CDK9 (1.00) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL20549695 | 0.84 | CCNT1 (0.61) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL18122690 | 0.84 | CDK7 (0.61) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL18122687 | 0.83 | CCNK (0.60) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL26516347 | 0.83 | CDK2 (0.66) | CCNT1CCNKCCNE1CDK2CDK7 | |
| SCHEMBL20286075 | 0.81 | CCNT1 (0.58) | CCNT1CCNKCCNE1CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3273966-B1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | DANA FARBER CANCER INST INC (US) | 2023-05-03 | — | — | EP | disclosed |