Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MAX | P61244 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342715 | 0.95 | MKNK2 (0.36) | GCKMKNK2CSNK1DSCN9AALDH1A1 | |
| SCHEMBL1343155 | 0.95 | GCK (0.41) | GCKMKNK2CSNK1DSCN5ASCN9A | |
| SCHEMBL2652270 | 0.92 | GCK (0.35) | GCKMKNK2MYCMAX | |
| SCHEMBL1342441 | 0.88 | MKNK2 (0.36) | GCKMKNK2SCN9ATRPV1MYC | |
| SCHEMBL1343475 | 0.88 | GCK (0.42) | GCKMKNK2SCN5ASCN9ATRPV1 | |
| SCHEMBL1340132 | 0.86 | MAPT (0.38) | CSNK1DMEN1ALDH1A1LMNAHTT | |
| SCHEMBL1343008 | 0.86 | MAPT (0.38) | CSNK1DMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL1341851 | 0.86 | MKNK2 (0.36) | GCKMKNK2CSNK1DALDH1A1TRPV1 | |
| SCHEMBL1341724 | 0.85 | KDM4E (0.38) | CSNK1DALDH1A1 | |
| SCHEMBL1340874 | 0.85 | KDM4E (0.38) | CSNK1DALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |