Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261507 | 0.86 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL11662720 | 0.83 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL3680376 | 0.82 | AOC3 (0.38) | SMN1; SMN2 | |
| SCHEMBL8781095 | 0.80 | ABCB1 (0.46) | ALDH1A1L3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL8781006 | 0.80 | SYK (0.47) | CYP1A2 | |
| SCHEMBL19665122 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL21859970 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| Hydrochloric Acid SCHEMBL17871947 | 0.79 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL147185 | 0.79 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL6055279 | 0.78 | PPARG (0.51) | ALDH1A1L3MBTL1MAPTNPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458382-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055482-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |