Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110179 | 0.95 | GAA (0.43) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26520352 | 0.89 | NPSR1 (0.41) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26520473 | 0.87 | KMT2A (0.41) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26520355 | 0.87 | KMT2A (0.41) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26519670 | 0.84 | NPSR1 (0.42) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26520350 | 0.84 | KMT2A (0.39) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26519854 | 0.83 | L3MBTL1 (0.37) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26520078 | 0.82 | L3MBTL1 (0.40) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26519673 | 0.82 | KMT2A (0.42) | KMT2AGAAL3MBTL1HTTTDP1 | |
| SCHEMBL26109601 | 0.82 | KMT2A (0.42) | KMT2AGAAL3MBTL1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196614-A1 | METHODS AND COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | AXONIS THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |