SCHEMBL265245

SCHEMBL265245

N#C[PH](=O)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265246 0.67
SCHEMBL27793276 0.67
SCHEMBL570369 0.52
Phosphonic Acid SCHEMBL29523497 0.48
Phosphonic Acid SCHEMBL28550339 0.48
Water SCHEMBL4461991 0.48
Phosphonic Acid SCHEMBL11044913 0.48
Water SCHEMBL28074298 0.48
Water SCHEMBL29693874 0.47
Magnesium Oxide SCHEMBL29351009 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040502-A Dicyanophosphine oxide monomer, and preparation method and application thereof 华中科技大学 2025-05-27 CN claimed
CN-120040502-A Dicyanophosphine oxide monomer, and preparation method and application thereof 华中科技大学 2025-05-27 CN disclosed
CN-120040502-A Dicyanophosphine oxide monomer, and preparation method and application thereof 华中科技大学 2025-05-27 CN disclosed
CN-120040502-A Dicyanophosphine oxide monomer, and preparation method and application thereof 华中科技大学 2025-05-27 CN disclosed
US-20250101006-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2025-03-27 US disclosed
EP-4472969-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS Novartis AG (CH) 2024-12-11 EP disclosed
CN-118871436-A Synthesis of pyrazolyl derivatives useful as anticancer agents 诺华股份有限公司 2024-10-29 CN disclosed
WO-2023143605-A1 PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2023-08-03 WO disclosed
EP-3297991-B1 NOVEL AMIDOHETEROARYL AROYL HYDRAZIDE ETHYNES SUN PHARMA ADVANCED RES CO LTD (IN) 2020-01-29 EP disclosed
US-10150733-B2 Amidoheteroaryl aroyl hydrazide ethynes SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2018-12-11 US disclosed
US-20060167015-A1 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol1yl)-3-(trifluoromethyl)phenyl]benzamide or an N-oxide or salts; anticarcinogenic agent (leukaemia) NOVARTIS AG (CH) 2006-07-27 US disclosed
US-20060142577-A1 Novel pyrimidineamide derivatives and the use thereof NOVARTIS AG (CH) 2006-06-29 US disclosed
EP-1546127-A1 NOVEL PYRIMIDINEAMIDE DERIVATIVES AND THE USE THEREOF Novartis AG (CH) 2005-06-29 EP disclosed
EP-1532138-A1 INHIBITORS OF TYROSINE KINASES Novartis AG (CH) 2005-05-25 EP disclosed
WO-2004029038-A1 NOVEL PYRIMIDINEAMIDE DERIVATIVES AND THE USE THEREOF NOVARTIS AG (CH) 2004-04-08 WO disclosed
WO-2004005281-A1 INHIBITORS OF TYROSINE KINASES NOVARTIS AG (CH) 2004-01-15 WO disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
WO-1998038168-A1 ISOQUINOLINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 1998-09-03 WO disclosed