Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1565887 | 1.00 | S1PR1 (0.46) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL1565008 | 0.83 | MAPT (0.44) | KMT2AMEN1ALDH1A1FFAR2TSHR | |
| SCHEMBL1566264 | 0.80 | FFAR2 (0.52) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL1565411 | 0.79 | HPGD (0.41) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL1566440 | 0.76 | FFAR2 (0.55) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL9071875 | 0.75 | S1PR1 (0.60) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL9071942 | 0.73 | S1PR1 (0.49) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL1566890 | 0.72 | S1PR1 (0.48) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL2646822 | 0.68 | KCNH2 (0.59) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL2645314 | 0.68 | KCNH2 (0.59) | S1PR1S1PR3KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458382-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055482-A1 | AMIDE DERIVATIVES AS GK ACTIVATORS | NOVO NORDISK A/S (DK) | 2003-07-10 | — | — | WO | disclosed |