Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299019 | 0.93 | LMNA (0.42) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL12016691 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL30807114 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL132981 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL29865503 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL17928303 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL132071 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL29842660 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL29511972 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL9927121 | 0.88 | LMNA (0.39) | ESR1LMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138100-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2C19, ETV6, ESR1 | ESR1 3/4885LMNA 3424/4885HPGD 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.