SCHEMBL265264

SCHEMBL265264

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nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.42
GSTK1 Q9Y2Q3 1/20 0.42
TGFBR1 P36897 3/20 0.41
OPRD1 P41143 4/20 0.38
OPRM1 P35372 3/20 0.38
OPRK1 P41145 1/20 0.38
MME P08473 4/20 0.38
GLO1 Q04760 1/20 0.37
NOD1 Q9Y239 1/20 0.34
PRMT1 Q99873 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30679730 1.00 PTGS1 (0.42) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL265263 1.00 PTGS1 (0.42) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL30679729 1.00 PTGS1 (0.42) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29527284 0.97 TGFBR1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29420016 0.97 TGFBR1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29382390 0.97 TGFBR1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29528046 0.97 TGFBR1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29540545 0.97 PTGS1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29528171 0.97 TGFBR1 (0.43) PTGS1GSTK1TGFBR1OPRD1OPRM1
SCHEMBL29867949 0.94 PTGS1 (0.42) PTGS1GSTK1TGFBR1OPRD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US claimed
EP-4212542-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2023-07-19 EP claimed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN claimed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO claimed
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US disclosed
CN-115087662-B Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2023-09-26 CN disclosed
CN-114786704-B Active polypeptide compound 陕西麦科奥特科技有限公司 2023-08-25 CN disclosed
EP-4212542-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2023-07-19 EP disclosed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN disclosed
EP-4041278-A1 ACTIVE POLYPEPTIDE COMPOUND Shaanxi Micot Technology Limited Company (CN) 2022-08-17 EP disclosed
CN-114786704-A Active polypeptide compounds 陕西麦科奥特科技有限公司 2022-07-22 CN disclosed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO disclosed
US-20050187160-A1 Monopegylated growth hormone proteins BOLDER BIOTECHNOLOGY INC. (US) 2005-08-25 US disclosed
CN-1210400-C Methods for making proteins containing free cysteine residues BOLDER BIOTECHNOLOGY INC (US) 2005-07-13 CN disclosed
US-20050026834-A1 Methods for making proteins containing free cysteine residues BOLDER BIOTECHNOLOGY, INC. 2005-02-03 US disclosed
EP-1200124-A4 IMMUNOGLOBULIN FUSION PROTEINS BOLDER BIOTECHNOLOGY INC (US) 2004-09-29 EP disclosed
US-6753165-B1 FOR RESIDUES THAT DO NOT FORM DISULFIDE BOND BOLDER BIOTECHNOLOGY, INC. 2004-06-22 US disclosed
CN-1355842-A Methods for making proteins containing free cysteine residues BOLDER BIOTECHNOLOGY INC (US) 2002-06-26 CN disclosed
EP-1200124-A1 IMMUNOGLOBULIN FUSION PROTEINS Bolder Biotechnology, Inc. (US) 2002-05-02 EP disclosed
WO-2001003737-A1 IMMUNOGLOBULIN FUSION PROTEINS BOLDER BIOTECHNOLOGY INC. (US) 2001-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND CALCR, BID, CASR PTGS1 3213/4885GSTK1 3947/4885TGFBR1 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.