Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26527978 | 0.89 | NAMPT (0.44) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26527335 | 0.88 | NAMPT (0.45) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26528714 | 0.87 | NAMPT (0.44) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26526564 | 0.87 | NAMPT (0.44) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26527383 | 0.87 | NAMPT (0.44) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26527079 | 0.87 | NAMPT (0.41) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26527553 | 0.87 | NAMPT (0.41) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26528084 | 0.87 | NAMPT (0.41) | NAMPTGPR119HDAC1L3MBTL1GRM2 | |
| SCHEMBL26526923 | 0.86 | GRM2 (0.40) | NAMPTHDAC1L3MBTL1GRM2ROCK2 | |
| SCHEMBL26527249 | 0.85 | NAMPT (0.42) | NAMPTGPR119HDAC1L3MBTL1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089170-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |