Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26526564 | 0.89 | NAMPT (0.44) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527978 | 0.89 | NAMPT (0.44) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26528714 | 0.89 | NAMPT (0.44) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527383 | 0.89 | NAMPT (0.44) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26526412 | 0.88 | NAMPT (0.42) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527249 | 0.87 | NAMPT (0.42) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527148 | 0.85 | NAMPT (0.41) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26528233 | 0.85 | NAMPT (0.41) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527553 | 0.85 | NAMPT (0.41) | NAMPTROCK2BRD4GPR119HDAC1 | |
| SCHEMBL26527518 | 0.85 | NAMPT (0.45) | NAMPTROCK2BRD4GPR119HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089170-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |