Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.39 |
| ▸ | CDK2 | P24941 | 7/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341920 | 0.93 | CCNE1 (0.43) | CCNE1CDK2CDK5FFAR2CNR1 | |
| SCHEMBL1339808 | 0.93 | CCNE1 (0.38) | CCNE1CDK2CDK5FFAR2GRM4 | |
| SCHEMBL2652852 | 0.90 | CCNE1 (0.38) | CCNE1CDK2CDK5FFAR2CNR1 | |
| SCHEMBL1340794 | 0.90 | CCNE1 (0.42) | CCNE1CDK2CDK5FFAR2GRM4 | |
| SCHEMBL1341918 | 0.84 | CCNE1 (0.42) | CCNE1CDK2CDK5FFAR2CNR1 | |
| SCHEMBL1342533 | 0.83 | CCNE1 (0.41) | CCNE1CDK2CDK5FFAR2CNR1 | |
| SCHEMBL1341887 | 0.83 | CCNE1 (0.36) | CCNE1CDK2CDK5FFAR2GRM4 | |
| SCHEMBL1342501 | 0.82 | FFAR2 (0.40) | CCNE1CDK2CDK5FFAR2GRM4 | |
| SCHEMBL1343341 | 0.81 | GRM4 (0.42) | CCNE1CDK2CDK5FFAR2CNR1 | |
| SCHEMBL1342748 | 0.81 | CCNE1 (0.46) | CCNE1CDK2CDK5FFAR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |