SCHEMBL26529436

SCHEMBL26529436

CCCCOC(=O)C(C)CNC(C)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.40
HPGD P15428 3/20 0.38
TSHR P16473 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
EPHX1 P07099 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
LMNA P02545 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
ESR1 P03372 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPK1 P28482 1/20 0.37
NR1H2 P55055 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529688 0.93 KDM4E (0.37) ALDH1A1KDM4ECA1CA2EPHX1
SCHEMBL26529238 0.93 KDM4E (0.40) ALDH1A1KDM4EEPHX1ACHE
SCHEMBL11238256 0.87 ALDH1A1 (0.40) ALDH1A1ATMHPGDTSHRSMN1; SMN2
SCHEMBL26529433 0.82 GAA (0.38) ALDH1A1KDM4EHPGDRAB9ALMNA
SCHEMBL13679523 0.79 HRH3 (0.30) KDM4E
SCHEMBL8954874 0.79 ALDH1A1 (0.54) ALDH1A1ATMHPGDTSHRSMN1; SMN2
SCHEMBL13541256 0.79 ALDH1A1 (0.54) ALDH1A1ATMHPGDTSHRSMN1; SMN2
SCHEMBL310458 0.79 ALDH1A1 (0.54) ALDH1A1ATMHPGDTSHRSMN1; SMN2
SCHEMBL26529240 0.79 EPHX1 (0.35) ALDH1A1KDM4ESMN1; SMN2EPHX1ACHE
SCHEMBL26529438 0.79 SMN1; SMN2 (0.39) ALDH1A1KDM4EHPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321591-A1 Beta-Amino Carboxylate (BAC) Solvents for Enhanced CO2 Separations BATTELLE MEMORIAL INSTITUTE 2023-10-12 US disclosed
WO-2023192410-A1 BETA-AMINO CARBOXYLATE (BAC) SOLVENTS FOR ENHANCED CO2 SEPARATIONS BATTELLE MEMORIAL INSTITUTE (US) 2023-10-05 WO disclosed