Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20816367 | 0.98 | MAPK1 (0.31) | MAPK1HSD17B10TRPC3TRPC6PRCP | |
| SCHEMBL20858625 | 0.98 | MAPK1 (0.31) | MAPK1HSD17B10TRPC3TRPC6PRCP | |
| SCHEMBL19300040 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL20553202 | 0.64 | SLC18A3 (0.35) | — | |
| SCHEMBL31512744 | 0.64 | — | — | |
| SCHEMBL20552882 | 0.62 | CYP17A1 (0.32) | MAPK1HSD17B10 | |
| SCHEMBL20553024 | 0.61 | MAPK1 (0.36) | MAPK1HSD17B10 | |
| SCHEMBL8225739 | 0.59 | ADORA2A (0.35) | HSD17B10 | |
| SCHEMBL15706621 | 0.58 | ALDH1A1 (0.36) | HSD17B10 | |
| SCHEMBL17675657 | 0.57 | EPHX1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341437-A | Substituted pyrazine derivative and application thereof | 李寒 | 2021-02-09 | — | — | CN | disclosed |