SCHEMBL26529948

SCHEMBL26529948

Clc1cc(Cl)cc(-c2ccc3c(c2)c2cc(-c4cc(Cl)cc(Cl)c4)ccc2n3-c2ccccc2-c2ccccc2-c2ccccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.35
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
PDK2 Q15119 1/20 0.35
MAPK14 Q16539 1/20 0.35
EDNRA P25101 2/20 0.34
EDNRB P24530 1/20 0.34
PTPN1 P18031 1/20 0.33
DUSP3 P51452 1/20 0.33
CYP2A6 P11509 1/20 0.33
AKR1B1 P15121 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
PGR P06401 1/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
METAP2 P50579 1/20 0.32
MAP4K4 O95819 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529787 0.94 NR1H2 (0.40) NR1H2RXRARXRBPDK2MAPK14
SCHEMBL26529480 0.88 NPSR1 (0.38) MAPK14HTTSMN1; SMN2ALDH1A1TSPO
SCHEMBL24668214 0.87 MGLL (0.36) NR1H2MAPK14HTTSMN1; SMN2ALDH1A1
SCHEMBL24669175 0.85 NPSR1 (0.36) MAPK14HTTSMN1; SMN2ALDH1A1TSPO
SCHEMBL24668259 0.85 NPSR1 (0.36) MAPK14HTTSMN1; SMN2ALDH1A1TSPO
SCHEMBL24668239 0.85 MGLL (0.37) NR1H2MAPK14CYP2A6ALDH1A1NPSR1
SCHEMBL26529984 0.85 PTGES2 (0.37) PDK2EDNRAEDNRBPTPN1MAP4K4
SCHEMBL22876181 0.84 CYP1A2 (0.46) NR1H2MAPK14CYP2A6AKR1B1PTGDR2
SCHEMBL22876321 0.84 CYP1A2 (0.46) NR1H2MAPK14CYP2A6AKR1B1PTGDR2
SCHEMBL26529289 0.84 MGLL (0.38) NR1H2MAPK14HTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 NR1H2 1705/4885RXRA 1633/4885RXRB 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.