Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738019 | 0.80 | POLB (0.62) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL18357419 | 0.80 | POLB (0.58) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL21818744 | 0.79 | MAPK1 (0.40) | POLBALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL31714775 | 0.76 | POLB (0.67) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL24516943 | 0.73 | SMN1; SMN2 (0.53) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3736225 | 0.73 | POLB (0.63) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL21357773 | 0.72 | MAPT (0.53) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL23645338 | 0.72 | MAPT (0.53) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL24517706 | 0.72 | POLB (0.49) | POLBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL1583105 | 0.70 | ALDH1A1 (0.57) | POLBALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |