Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151633 | 1.00 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL25861971 | 1.00 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL13314619 | 0.86 | PIK3CD (0.30) | — | |
| SCHEMBL10177528 | 0.80 | — | — | |
| SCHEMBL25662328 | 0.77 | ALDH1A1 (0.39) | EPHX1 | |
| SCHEMBL8243723 | 0.76 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL25466186 | 0.73 | — | — | |
| SCHEMBL20205704 | 0.73 | — | — | |
| SCHEMBL8213949 | 0.73 | — | — | |
| SCHEMBL9888333 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180345-A1 | TRICYCLIC PHTHALAZINES AND DERIVATIVES AS SOS1 INHIBITORS | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-09-28 | — | — | WO | disclosed |