Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776384 | 1.00 | KRAS (0.35) | KRASHRH4GPR119EIF4EBP1 | |
| SCHEMBL27084380 | 0.91 | KRAS (0.37) | KRASHRH4EIF4EBP1 | |
| SCHEMBL30776423 | 0.88 | EIF4EBP1 (0.31) | KRASEIF4EBP1 | |
| SCHEMBL26113915 | 0.87 | KRAS (0.32) | KRASGPR119 | |
| SCHEMBL26533798 | 0.87 | GPR119 (0.35) | KRASGPR119 | |
| SCHEMBL30587246 | 0.87 | GPR119 (0.35) | KRASGPR119 | |
| SCHEMBL26533794 | 0.87 | GPR119 (0.35) | KRASGPR119 | |
| SCHEMBL26114010 | 0.87 | KRAS (0.34) | KRAS | |
| SCHEMBL30587289 | 0.87 | GPR119 (0.34) | KRASGPR119 | |
| SCHEMBL26532739 | 0.87 | GPR119 (0.34) | KRASGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183585-A1 | KRAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2023-09-28 | — | — | WO | disclosed |