Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.54 |
| ▸ | KDR | P35968 | 4/20 | 0.52 |
| ▸ | KIT | P10721 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31137783 | 1.00 | EGFR (0.54) | EGFRKDRKIT | |
| SCHEMBL30891753 | 0.93 | KIT (0.47) | EGFRKDRKIT | |
| SCHEMBL26535333 | 0.93 | KIT (0.47) | EGFRKDRKIT | |
| SCHEMBL26535443 | 0.92 | PDGFRB (0.47) | EGFRKDRKIT | |
| SCHEMBL30891776 | 0.92 | PDGFRB (0.47) | EGFRKDRKIT | |
| SCHEMBL30394725 | 0.90 | KDR (0.52) | EGFRKDRKIT | |
| SCHEMBL29238265 | 0.90 | KDR (0.52) | EGFRKDRKIT | |
| SCHEMBL26535380 | 0.88 | KIT (0.46) | KDRKIT | |
| SCHEMBL30891757 | 0.88 | KIT (0.46) | KDRKIT | |
| SCHEMBL29238264 | 0.88 | KDR (0.53) | EGFRKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |