Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 12/20 | 0.44 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | FLT4 | P35916 | 3/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891757 | 1.00 | KIT (0.46) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL26535383 | 0.91 | PDGFRB (0.47) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL30395160 | 0.91 | PDGFRB (0.47) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL30394202 | 0.88 | KIT (0.45) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL26101328 | 0.88 | KIT (0.45) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL29238243 | 0.88 | KIT (0.45) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL29238221 | 0.88 | KIT (0.45) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL26535844 | 0.88 | KIT (0.45) | KITPDGFRBFLT3KDRFLT4 | |
| SCHEMBL31137783 | 0.88 | EGFR (0.54) | KITKDR | |
| SCHEMBL26535296 | 0.88 | EGFR (0.54) | KITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |