Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.55 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394637 | 1.00 | KDR (0.55) | KDREGFRPDGFRBFLT4AURKA | |
| SCHEMBL26102568 | 0.91 | KDR (0.53) | KDREGFRPDGFRBFLT4HDAC1 | |
| SCHEMBL26100255 | 0.88 | KDR (0.49) | KDREGFRPDGFRBFLT4AURKA | |
| SCHEMBL26098752 | 0.85 | PDGFRB (0.54) | KDREGFRPDGFRBFLT4HDAC3 | |
| SCHEMBL30394508 | 0.85 | PDGFRB (0.54) | KDREGFRPDGFRBFLT4HDAC3 | |
| SCHEMBL26102256 | 0.84 | PDGFRB (0.51) | KDREGFRPDGFRBFLT4CSF1R | |
| SCHEMBL26102182 | 0.81 | KDR (0.51) | KDREGFRPDGFRBFLT4AURKB | |
| SCHEMBL30393191 | 0.81 | KDR (0.47) | KDREGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL26098887 | 0.81 | KDR (0.47) | KDREGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL30394611 | 0.80 | KDR (0.54) | KDREGFRPDGFRBFLT4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |