Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.47 |
| ▸ | EGFR | P00533 | 7/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098887 | 1.00 | KDR (0.47) | KDREGFRKITHDAC3HDAC4 | |
| SCHEMBL26101918 | 0.91 | MCHR1 (0.48) | KDREGFRKIT | |
| SCHEMBL26102229 | 0.87 | EGFR (0.44) | KDREGFRKITERBB2 | |
| SCHEMBL26132963 | 0.83 | KDR (0.46) | KDREGFRKIT | |
| SCHEMBL30394637 | 0.81 | KDR (0.55) | KDREGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL26535641 | 0.81 | KDR (0.55) | KDREGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL30394282 | 0.80 | KIT (0.43) | KDREGFRKITHDAC3HDAC4 | |
| SCHEMBL26099737 | 0.79 | BRAF (0.46) | KDRKIT | |
| SCHEMBL26102835 | 0.79 | KIT (0.43) | KDREGFRKITHDAC3HDAC4 | |
| SCHEMBL26100822 | 0.77 | BRAF (0.43) | KDRKITPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |