SCHEMBL26535804

SCHEMBL26535804

c1ccc(N(c2ccc3ccccc3c2)c2ccc3ccc4ccccc4c3c2N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 5/20 0.32
HSD17B10 Q99714 4/20 0.32
ALDH1A1 P00352 4/20 0.32
HIF1A Q16665 2/20 0.32
HPGD P15428 2/20 0.32
CYP1B1 Q16678 1/20 0.32
THRB P10828 1/20 0.32
TSHR P16473 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP2A6 P11509 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2D6 P10635 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
FYN P06241 2/20 0.30
AHR P35869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26534686 0.91 ALDH1A1 (0.38) KDM4ECYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL24048467 0.88 ABCG2 (0.37) KDM4ECYP1A2HSD17B10ALDH1A1HPGD
SCHEMBL24047989 0.87 NQO1 (0.32)
SCHEMBL258997 0.86 ALDH1A1 (0.36) KDM4ECYP1A2HSD17B10ALDH1A1HPGD
SCHEMBL29478361 0.86 ALDH1A1 (0.36) KDM4ECYP1A2HSD17B10ALDH1A1HPGD
SCHEMBL24047424 0.84 ABCG2 (0.40) KDM4ECYP1A2HSD17B10ALDH1A1HPGD
SCHEMBL24066531 0.84 ALDH1A1 (0.34) KDM4ECYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL17342394 0.83 ALDH1A1 (0.38) KDM4ECYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL1753896 0.82 KDM4E (0.37) KDM4ECYP1A2HSD17B10ALDH1A1HIF1A
SCHEMBL24472841 0.82 HSD17B10 (0.33) KDM4ECYP1A2HSD17B10ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023075157-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2023-05-04 WO disclosed