Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068832 | 0.84 | GPR119 (0.35) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL14860682 | 0.81 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL5172212 | 0.79 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL1097122 | 0.78 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL6172899 | 0.78 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL23376785 | 0.78 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL24915163 | 0.78 | GPR119 (0.38) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL30437740 | 0.78 | MEN1 (0.42) | GPR119MEN1KMT2AALDH1A1 | |
| SCHEMBL5849847 | 0.77 | GPR119 (0.37) | GPR119MEN1KMT2ABCHEPOLB | |
| SCHEMBL2471937 | 0.77 | GPR119 (0.37) | GPR119MEN1KMT2ABCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |