⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320142 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL29187107 | 0.87 | BTK (0.39) | — | |
| SCHEMBL21613585 | 0.83 | KDR (0.42) | — | |
| SCHEMBL27919468 | 0.78 | — | — | |
| SCHEMBL20530268 | 0.78 | — | — | |
| SCHEMBL20530267 | 0.76 | — | — | |
| SCHEMBL16288697 | 0.73 | — | — | |
| SCHEMBL29440483 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL5789919 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL8233042 | 0.73 | F2R (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512085-B2 | Heteroaryl compound having drug activity | SHANGHAI DUDE MEDICAL TECHNOLOGY CO., LTD (CN) | 2022-11-29 | — | — | US | disclosed |
| EP-3643716-B1 | HETEROARYL COMPOUND HAVING PHARMACEUTICAL ACTIVITY | SHANGHAI DUDE MEDICAL TECH CO LTD (CN) | 2022-05-04 | — | — | EP | disclosed |
| CN-109111446-B | Heteroaryl compound with pharmaceutical activity | 上海度德医药科技有限公司 | 2021-11-30 | — | — | CN | disclosed |
| EP-3643716-A1 | HETEROARYL COMPOUND HAVING PHARMACEUTICAL ACTIVITY | Shanghai Dude Medical Technology Co., Ltd (CN) | 2020-04-29 | — | — | EP | disclosed |
| US-20200123156-A1 | HETEROARYL COMPOUND HAVING DRUG ACTIVITY | SHANGHAI DUDE MEDICAL TECHNOLOGY CO., LTD | 2020-04-23 | — | — | US | disclosed |
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2714041-B1 | ARYLOXYMETHYL CYCLOPROPANE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-2748151-B1 | PYRIMIDINE PDE10 INHIBITORS | MERCK SHARP & DOHME (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9062059-B2 | Pyrimidine PDE10 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062059-B2 | Pyrimidine PDE10 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-06-23 | — | — | US | disclosed |
| WO-2012162213-A1 | ARYLOXYMETHYL CYCLOPROPANE DERIVATIVES AS PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-11-29 | — | — | WO | disclosed |
| US-8133909-B2 | Heteroaromatic monoamides as orexinin receptor antagonists | HOFFMANN-LA ROCHE INC. (US) | 2012-03-13 | — | — | US | disclosed |
| CN-102066325-A | Heteroaromatic monoamides as orexin receptor antagonists | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | disclosed |
| EP-2297102-A1 | HETEROAROMATIC MONOAMIDES AS OREXININ RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009153180-A1 | HETEROAROMATIC MONOAMIDES AS OREXININ RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-23 | — | — | WO | disclosed |
| US-20090312314-A1 | HETEROAROMATIC MONOAMIDES AS OREXININ RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-17 | — | — | US | disclosed |
| US-7566781-B2 | Imidazopyridine compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-20070249659-A1 | melanin concentrating hormone receptor antagonist; preventing or treating vascular system diseases, nervous system disorders, metabolic disorders, urogenital diseases, respiratory diseases disorders; N-(2-ethyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide | BANYU PHARMACEUTICAL., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| CN-1950372-A | imidazopyridine compounds | BANYU PHARMA CO LTD (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-1748048-A1 | IMIDAZOPYRIDINE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-31 | — | — | EP | disclosed |