Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622850 | 0.71 | LMNA (0.56) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL23505741 | 0.70 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL19861950 | 0.68 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL17236510 | 0.68 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL1105467 | 0.68 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL24070337 | 0.68 | CA12 (0.41) | LMNASMN1; SMN2CA12CA1CA9 | |
| SCHEMBL8252369 | 0.67 | — | — | |
| SCHEMBL20049899 | 0.67 | SMN1; SMN2 (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL14525969 | 0.67 | — | — | |
| SCHEMBL15805489 | 0.67 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187783-A1 | COMPOUNDS USABLE AS MODULATORS OF PERK ACTIVITY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-10-05 | — | — | WO | disclosed |