Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651325 | 0.99 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL2651937 | 0.94 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL2651993 | 0.92 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL2654041 | 0.88 | PPARA (0.48) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9347912 | 0.86 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9347717 | 0.84 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL10613234 | 0.84 | SMN1; SMN2 (0.65) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL4037850 | 0.83 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL1549725 | 0.82 | PPARA (0.50) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL30633001 | 0.82 | PPARA (0.50) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758859-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118542-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-15 | — | — | WO | disclosed |