SCHEMBL26539344

SCHEMBL26539344

c1ccc(-n2c3ccccc3c3cc(N(c4ccc5c6ccccc6n(-c6ccccc6)c5c4)c4cccc5c4c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
KDR P35968 1/20 0.32
REN P00797 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26539096 0.96 L3MBTL1 (0.50) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904406 0.94 KDM4E (0.47) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539349 0.94 KDM4E (0.47) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539348 0.92 KDM4E (0.46) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539624 0.92 KDM4E (0.41) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539067 0.90 L3MBTL1 (0.44) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904363 0.90 JAK2 (0.46) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904310 0.89 KDM4E (0.43) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26540222 0.89 L3MBTL1 (0.43) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539063 0.89 KDM4E (0.43) KDM4EATML3MBTL1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023185078-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-10-05 WO disclosed