Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | HRH2 | P25021 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000122 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL354446 | 0.80 | — | — | |
| Valine SCHEMBL2651986 | 0.75 | SLC7A5 (0.47) | CSNK2A1NOS1ALDH1A1HPGDALOX15 | |
| SCHEMBL5875680 | 0.72 | HDAC6 (0.54) | CSNK2A1NOS1ALDH1A1HPGDALOX15 | |
| SCHEMBL1631557 | 0.66 | — | — | |
| Trifluoroacetic Acid SCHEMBL4060317 | 0.66 | HSP90AA1 (0.55) | ALDH1A1ALOX15TSHR | |
| SCHEMBL2140479 | 0.66 | — | — | |
| Trifluoroacetic Acid SCHEMBL2267588 | 0.65 | ALDH1A1 (0.44) | NOS1ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL4442697 | 0.64 | HCAR2 (0.43) | HRH4HRH3ALDH1A1 | |
| Water SCHEMBL28159942 | 0.64 | HCAR2 (0.55) | CSNK2A1NOS1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015358-A1 | Fluorination Process of Protected Aminothiazole | PROSIDION LIMITED (GB) | 2008-01-17 | — | — | US | disclosed |
| EP-1778657-A1 | FLUORINATION PROCESS OF PROTECTED AMINOTHIAZOLE | Prosidion Ltd. (GB) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006016174-A1 | FLUORINATION PROCESS OF PROTECTED AMINOTHIAZOLE | PROSIDION LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015358-A1 | Fluorination Process of Protected Aminothiazole | GCK, KHK, GCKR | CSNK2A1 183/4885HRH4 4596/4885HRH3 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.