⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373455 | 0.71 | ADH1B (0.32) | — | |
| SCHEMBL12534579 | 0.71 | — | — | |
| SCHEMBL10642205 | 0.67 | — | — | |
| SCHEMBL5547568 | 0.63 | — | — | |
| SCHEMBL9509608 | 0.61 | — | — | |
| SCHEMBL3728774 | 0.61 | — | — | |
| Dimethylformamide SCHEMBL5753147 | 0.59 | TSHR (0.56) | — | |
| SCHEMBL29261029 | 0.57 | — | — | |
| SCHEMBL15195782 | 0.57 | — | — | |
| SCHEMBL1556089 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078168-A1 | PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2007-04-05 | — | — | US | disclosed |
| CN-1898209-A | Pyridinecarboxylic acid derivatives as glucokinase modulators | ASTRAZENECA AB (SE) | 2007-01-17 | — | — | CN | disclosed |
| EP-1682509-A1 | PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS | AstraZeneca AB (SE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044801-A1 | PYRIDINE CARBOXYLIC ACID DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | disclosed |